TissueBlue shown to have superior safety profile
Articles - 2020-05-03
Animal studies have shown the dose-dependent toxicity of indocyanine green, especially in case of diffusion into the subretinal space, where it can potentially cause severe retinal damage. In fact, because of the altered structure of the neuroretina, iatrogenic retinal breaks may allow indocyanine green to reach the sub-retinal space. In contrast, the safety proﬁle of brilliant blue G is excellent, showing no toxicities in human and animal studies.